Most artificial cannabinoids are agonists on the cannabinoid receptors. They have been built to be similar to THC,[nine] the all-natural cannabinoid Together with the strongest binding affinity into the CB1 receptor, which can be linked to the psychoactive consequences or "high" of marijuana.[ten] These artificial analogs usually have increased binding affinity and better potency into the CB1 receptors.
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The effects of smoking cigarettes spice are just like those of marijuana, the primary reason people today use Spice is that it's unobtrusive. It can be processed by sprinkling synthetic guy-built substances on destroyed, dried plant material.
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It provides a protracted-lasting high and is neat and Secure to work with. K2 Spice Store’s supply is speedy, as well as their customer service may be very Skilled.
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